Rational Design of Aza Sugars via Biocatalysis: Mannojirimycin and Other Glycosidase Inhibitors

Tomas Hudlicky, Jacques Rouden, Hector Luna

Resultado de la investigación: Contribución a una revistaArtículo

52 Citas (Scopus)

Resumen

Mannojirymicin 2a, its C-5 epimer 13, and mannosidase inhibitor 3a have been synthesized from chlorobenzene via enzymatic hydroxylation followed by stereoselective amination and oxidative cleavage of the 1-chlorocyclohexa-4,5-diene-2,3-diol.

Idioma originalInglés
Páginas (desde-hasta)985-987
Número de páginas3
PublicaciónJournal of Organic Chemistry
Volumen58
N.º5
DOI
EstadoPublicada - 26 feb 1993

Huella dactilar

Mannosidases
Amination
Hydroxylation
Glycoside Hydrolases
Sugars
chlorobenzene
Biocatalysis

Citar esto

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Rational Design of Aza Sugars via Biocatalysis : Mannojirimycin and Other Glycosidase Inhibitors. / Hudlicky, Tomas; Rouden, Jacques; Luna, Hector.

En: Journal of Organic Chemistry, Vol. 58, N.º 5, 26.02.1993, p. 985-987.

Resultado de la investigación: Contribución a una revistaArtículo

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AU - Luna, Hector

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