Biological hazard evaluation of a pharmaceutical effluent before and after a photo-Fenton treatment

Karen Adriana Novoa-Luna, Arisbeht Mendoza-Zepeda, Reyna Natividad Rangel, Rubi Romero, Marcela Galar-Martínez, Leobardo Manuel Gómez-Oliván

Resultado de la investigación: Contribución a una revistaArtículo

9 Citas (Scopus)

Resumen

The aim of this study was to evaluate the biological hazard of a pharmaceutical effluent before and after treatment. For the former, the determined 96 h-LC50 value was 1.2%. The photo-Fenton treatment catalyzed with an iron-pillared clay reduced this parameter by 341.7%. Statistically significant increases with respect to the control group (P < 0.05) were observed at 12, 24, 48 and 72 h in HPC (50.2, 30.4, 66.9 and 43.3%), LPX (22, 83.2, 62.7 and 59.5%) and PCC (14.6, 23.6, 24.4 and 25.6%) and antioxidant enzymes SOD (29.4, 38.5, 32.7 and 49.5%) and CAT (48.4, 50.3, 38.8 and 46.1%) in Hyalella azteca before treatment. Also increases in damage index were observed before treatment of 53.1, 59.9, 66.6 and 72.1% at 12, 24, 48 and 72 h, respectively. After treatment the same biomarkers of oxidative stress decreased with respect to before treatment being to HPC (29.3, 22.5, 41.6 and 31.7%); LPX (14.2, 43.1, 30.7 and 35.5%); PCC (12.6, 21.3, 24.2 and 23.9%); SOD (39.2, 33.9, 49.5 and 37.9%) and CAT (28.6, 35.8, 33.7 and 31.7) at 12, 24, 48 and 72 h, respectively (P < 0.05). The damage index were decreased at 12, 24, 48 and 72 h in 48.9, 57.8, 67.3 and 72.1%, respectively. In conclusion, the obtained results demonstrate the need of performing bioassays in order to characterize an effluent before discharge and not base such a decision only upon current normativity. In addition, it was also concluded that the heterogeneous photo-Fenton process decreases the presence of PCT, oxidative stress, genotoxic damage and LC50 in Hyalella azteca.

Idioma originalInglés
Páginas (desde-hasta)830-840
Número de páginas11
PublicaciónScience of the Total Environment
Volumen569-570
DOI
EstadoPublicada - 1 nov 2016

Huella dactilar

Oxidative stress
Drug products
Effluents
Hazards
drug
hazard
effluent
damage
Bioassay
Biomarkers
Antioxidants
pillared clay
Pharmaceutical Preparations
Clay
Iron
Enzymes
antioxidant
biomarker
bioassay
enzyme

Citar esto

Novoa-Luna, Karen Adriana ; Mendoza-Zepeda, Arisbeht ; Natividad Rangel, Reyna ; Romero, Rubi ; Galar-Martínez, Marcela ; Gómez-Oliván, Leobardo Manuel. / Biological hazard evaluation of a pharmaceutical effluent before and after a photo-Fenton treatment. En: Science of the Total Environment. 2016 ; Vol. 569-570. pp. 830-840.
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title = "Biological hazard evaluation of a pharmaceutical effluent before and after a photo-Fenton treatment",
abstract = "The aim of this study was to evaluate the biological hazard of a pharmaceutical effluent before and after treatment. For the former, the determined 96 h-LC50 value was 1.2{\%}. The photo-Fenton treatment catalyzed with an iron-pillared clay reduced this parameter by 341.7{\%}. Statistically significant increases with respect to the control group (P < 0.05) were observed at 12, 24, 48 and 72 h in HPC (50.2, 30.4, 66.9 and 43.3{\%}), LPX (22, 83.2, 62.7 and 59.5{\%}) and PCC (14.6, 23.6, 24.4 and 25.6{\%}) and antioxidant enzymes SOD (29.4, 38.5, 32.7 and 49.5{\%}) and CAT (48.4, 50.3, 38.8 and 46.1{\%}) in Hyalella azteca before treatment. Also increases in damage index were observed before treatment of 53.1, 59.9, 66.6 and 72.1{\%} at 12, 24, 48 and 72 h, respectively. After treatment the same biomarkers of oxidative stress decreased with respect to before treatment being to HPC (29.3, 22.5, 41.6 and 31.7{\%}); LPX (14.2, 43.1, 30.7 and 35.5{\%}); PCC (12.6, 21.3, 24.2 and 23.9{\%}); SOD (39.2, 33.9, 49.5 and 37.9{\%}) and CAT (28.6, 35.8, 33.7 and 31.7) at 12, 24, 48 and 72 h, respectively (P < 0.05). The damage index were decreased at 12, 24, 48 and 72 h in 48.9, 57.8, 67.3 and 72.1{\%}, respectively. In conclusion, the obtained results demonstrate the need of performing bioassays in order to characterize an effluent before discharge and not base such a decision only upon current normativity. In addition, it was also concluded that the heterogeneous photo-Fenton process decreases the presence of PCT, oxidative stress, genotoxic damage and LC50 in Hyalella azteca.",
keywords = "Amphipod, Fe-PILC, Hyalella azteca, Oxidative stress, Paracetamol, Photo-Fenton process",
author = "Novoa-Luna, {Karen Adriana} and Arisbeht Mendoza-Zepeda and {Natividad Rangel}, Reyna and Rubi Romero and Marcela Galar-Mart{\'i}nez and G{\'o}mez-Oliv{\'a}n, {Leobardo Manuel}",
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Biological hazard evaluation of a pharmaceutical effluent before and after a photo-Fenton treatment. / Novoa-Luna, Karen Adriana; Mendoza-Zepeda, Arisbeht; Natividad Rangel, Reyna; Romero, Rubi; Galar-Martínez, Marcela; Gómez-Oliván, Leobardo Manuel.

En: Science of the Total Environment, Vol. 569-570, 01.11.2016, p. 830-840.

Resultado de la investigación: Contribución a una revistaArtículo

TY - JOUR

T1 - Biological hazard evaluation of a pharmaceutical effluent before and after a photo-Fenton treatment

AU - Novoa-Luna, Karen Adriana

AU - Mendoza-Zepeda, Arisbeht

AU - Natividad Rangel, Reyna

AU - Romero, Rubi

AU - Galar-Martínez, Marcela

AU - Gómez-Oliván, Leobardo Manuel

PY - 2016/11/1

Y1 - 2016/11/1

N2 - The aim of this study was to evaluate the biological hazard of a pharmaceutical effluent before and after treatment. For the former, the determined 96 h-LC50 value was 1.2%. The photo-Fenton treatment catalyzed with an iron-pillared clay reduced this parameter by 341.7%. Statistically significant increases with respect to the control group (P < 0.05) were observed at 12, 24, 48 and 72 h in HPC (50.2, 30.4, 66.9 and 43.3%), LPX (22, 83.2, 62.7 and 59.5%) and PCC (14.6, 23.6, 24.4 and 25.6%) and antioxidant enzymes SOD (29.4, 38.5, 32.7 and 49.5%) and CAT (48.4, 50.3, 38.8 and 46.1%) in Hyalella azteca before treatment. Also increases in damage index were observed before treatment of 53.1, 59.9, 66.6 and 72.1% at 12, 24, 48 and 72 h, respectively. After treatment the same biomarkers of oxidative stress decreased with respect to before treatment being to HPC (29.3, 22.5, 41.6 and 31.7%); LPX (14.2, 43.1, 30.7 and 35.5%); PCC (12.6, 21.3, 24.2 and 23.9%); SOD (39.2, 33.9, 49.5 and 37.9%) and CAT (28.6, 35.8, 33.7 and 31.7) at 12, 24, 48 and 72 h, respectively (P < 0.05). The damage index were decreased at 12, 24, 48 and 72 h in 48.9, 57.8, 67.3 and 72.1%, respectively. In conclusion, the obtained results demonstrate the need of performing bioassays in order to characterize an effluent before discharge and not base such a decision only upon current normativity. In addition, it was also concluded that the heterogeneous photo-Fenton process decreases the presence of PCT, oxidative stress, genotoxic damage and LC50 in Hyalella azteca.

AB - The aim of this study was to evaluate the biological hazard of a pharmaceutical effluent before and after treatment. For the former, the determined 96 h-LC50 value was 1.2%. The photo-Fenton treatment catalyzed with an iron-pillared clay reduced this parameter by 341.7%. Statistically significant increases with respect to the control group (P < 0.05) were observed at 12, 24, 48 and 72 h in HPC (50.2, 30.4, 66.9 and 43.3%), LPX (22, 83.2, 62.7 and 59.5%) and PCC (14.6, 23.6, 24.4 and 25.6%) and antioxidant enzymes SOD (29.4, 38.5, 32.7 and 49.5%) and CAT (48.4, 50.3, 38.8 and 46.1%) in Hyalella azteca before treatment. Also increases in damage index were observed before treatment of 53.1, 59.9, 66.6 and 72.1% at 12, 24, 48 and 72 h, respectively. After treatment the same biomarkers of oxidative stress decreased with respect to before treatment being to HPC (29.3, 22.5, 41.6 and 31.7%); LPX (14.2, 43.1, 30.7 and 35.5%); PCC (12.6, 21.3, 24.2 and 23.9%); SOD (39.2, 33.9, 49.5 and 37.9%) and CAT (28.6, 35.8, 33.7 and 31.7) at 12, 24, 48 and 72 h, respectively (P < 0.05). The damage index were decreased at 12, 24, 48 and 72 h in 48.9, 57.8, 67.3 and 72.1%, respectively. In conclusion, the obtained results demonstrate the need of performing bioassays in order to characterize an effluent before discharge and not base such a decision only upon current normativity. In addition, it was also concluded that the heterogeneous photo-Fenton process decreases the presence of PCT, oxidative stress, genotoxic damage and LC50 in Hyalella azteca.

KW - Amphipod

KW - Fe-PILC

KW - Hyalella azteca

KW - Oxidative stress

KW - Paracetamol

KW - Photo-Fenton process

UR - http://www.scopus.com/inward/record.url?scp=84989954281&partnerID=8YFLogxK

U2 - 10.1016/j.scitotenv.2016.06.086

DO - 10.1016/j.scitotenv.2016.06.086

M3 - Artículo

C2 - 27392336

AN - SCOPUS:84989954281

VL - 569-570

SP - 830

EP - 840

JO - Science of the Total Environment

JF - Science of the Total Environment

SN - 0048-9697

ER -