Application of factorial experimental design on the optical absorption from glucose–insulin samples in mid-infrared spectroscopy

G. Romo-Cárdenas, J. de D. Sánchez-López, P. A. Luque, C. M. Gómez-Gutiérrez, Juan I. Nieto-Hipólito, Santiago Camacho Lopez, Arturo Jiménez-Cruz, C. Gastelum-Acosta, M. Vázquez-Briseño, C. Navarro-Cota

Resultado de la investigación: Contribución a una revistaArtículo

Resumen

An important challenge to be addressed in the search for an optically based, non-invasive blood glucose quantification method, is related to the spectral interference between glucose and insulin in the mid-infrared region. This work proposes the use of a factorial experimental design in order to understand the optical overlapping of these compounds. The results show how in the 1100–950 cm −1 range, glucose has a greater contribution than insulin to the absorption spectrum, without a significant effect from their interaction. These results and the use of the proposed technique could bring in interesting insights for biomedical applications.

Idioma originalInglés
Número de artículo102170
PublicaciónResults in Physics
Volumen13
DOI
EstadoPublicada - 1 jun 2019

Huella dactilar

glucose
insulin
optical absorption
infrared spectroscopy
blood
absorption spectra
interference
interactions

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Romo-Cárdenas, G., Sánchez-López, J. D. D., Luque, P. A., Gómez-Gutiérrez, C. M., Nieto-Hipólito, J. I., Camacho Lopez, S., ... Navarro-Cota, C. (2019). Application of factorial experimental design on the optical absorption from glucose–insulin samples in mid-infrared spectroscopy. Results in Physics, 13, [102170]. https://doi.org/10.1016/j.rinp.2019.102170
Romo-Cárdenas, G. ; Sánchez-López, J. de D. ; Luque, P. A. ; Gómez-Gutiérrez, C. M. ; Nieto-Hipólito, Juan I. ; Camacho Lopez, Santiago ; Jiménez-Cruz, Arturo ; Gastelum-Acosta, C. ; Vázquez-Briseño, M. ; Navarro-Cota, C. / Application of factorial experimental design on the optical absorption from glucose–insulin samples in mid-infrared spectroscopy. En: Results in Physics. 2019 ; Vol. 13.
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title = "Application of factorial experimental design on the optical absorption from glucose–insulin samples in mid-infrared spectroscopy",
abstract = "An important challenge to be addressed in the search for an optically based, non-invasive blood glucose quantification method, is related to the spectral interference between glucose and insulin in the mid-infrared region. This work proposes the use of a factorial experimental design in order to understand the optical overlapping of these compounds. The results show how in the 1100–950 cm −1 range, glucose has a greater contribution than insulin to the absorption spectrum, without a significant effect from their interaction. These results and the use of the proposed technique could bring in interesting insights for biomedical applications.",
keywords = "Factorial experimental design, Glucose - insulin, Non-invasive blood glucose quantification, mid-IR spectroscopy",
author = "G. Romo-C{\'a}rdenas and S{\'a}nchez-L{\'o}pez, {J. de D.} and Luque, {P. A.} and G{\'o}mez-Guti{\'e}rrez, {C. M.} and Nieto-Hip{\'o}lito, {Juan I.} and {Camacho Lopez}, Santiago and Arturo Jim{\'e}nez-Cruz and C. Gastelum-Acosta and M. V{\'a}zquez-Brise{\~n}o and C. Navarro-Cota",
year = "2019",
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language = "Ingl{\'e}s",
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Romo-Cárdenas, G, Sánchez-López, JDD, Luque, PA, Gómez-Gutiérrez, CM, Nieto-Hipólito, JI, Camacho Lopez, S, Jiménez-Cruz, A, Gastelum-Acosta, C, Vázquez-Briseño, M & Navarro-Cota, C 2019, 'Application of factorial experimental design on the optical absorption from glucose–insulin samples in mid-infrared spectroscopy', Results in Physics, vol. 13, 102170. https://doi.org/10.1016/j.rinp.2019.102170

Application of factorial experimental design on the optical absorption from glucose–insulin samples in mid-infrared spectroscopy. / Romo-Cárdenas, G.; Sánchez-López, J. de D.; Luque, P. A.; Gómez-Gutiérrez, C. M.; Nieto-Hipólito, Juan I.; Camacho Lopez, Santiago; Jiménez-Cruz, Arturo; Gastelum-Acosta, C.; Vázquez-Briseño, M.; Navarro-Cota, C.

En: Results in Physics, Vol. 13, 102170, 01.06.2019.

Resultado de la investigación: Contribución a una revistaArtículo

TY - JOUR

T1 - Application of factorial experimental design on the optical absorption from glucose–insulin samples in mid-infrared spectroscopy

AU - Romo-Cárdenas, G.

AU - Sánchez-López, J. de D.

AU - Luque, P. A.

AU - Gómez-Gutiérrez, C. M.

AU - Nieto-Hipólito, Juan I.

AU - Camacho Lopez, Santiago

AU - Jiménez-Cruz, Arturo

AU - Gastelum-Acosta, C.

AU - Vázquez-Briseño, M.

AU - Navarro-Cota, C.

PY - 2019/6/1

Y1 - 2019/6/1

N2 - An important challenge to be addressed in the search for an optically based, non-invasive blood glucose quantification method, is related to the spectral interference between glucose and insulin in the mid-infrared region. This work proposes the use of a factorial experimental design in order to understand the optical overlapping of these compounds. The results show how in the 1100–950 cm −1 range, glucose has a greater contribution than insulin to the absorption spectrum, without a significant effect from their interaction. These results and the use of the proposed technique could bring in interesting insights for biomedical applications.

AB - An important challenge to be addressed in the search for an optically based, non-invasive blood glucose quantification method, is related to the spectral interference between glucose and insulin in the mid-infrared region. This work proposes the use of a factorial experimental design in order to understand the optical overlapping of these compounds. The results show how in the 1100–950 cm −1 range, glucose has a greater contribution than insulin to the absorption spectrum, without a significant effect from their interaction. These results and the use of the proposed technique could bring in interesting insights for biomedical applications.

KW - Factorial experimental design

KW - Glucose - insulin

KW - Non-invasive blood glucose quantification

KW - mid-IR spectroscopy

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