2-Hydroxynaphthoquinones. Synthesis, electrochemical study, and biological essays of activity

César R. Solorio-Alvarado, Eduardo Peña-Cabrera, Jesús García-Soto, Juana López-Godínez, Felipe J. González, Alejandro Álvarez-Hernández

Resultado de la investigación: Contribución a una revistaArtículo

7 Citas (Scopus)

Resumen

The synthesis of nine 2-hydroxynaphthoquinones was achieved starting from squaric acid esters. The electrochemical and biological evaluations of these compounds were tested using the sea urchin ovules as a model. An interesting correlation between structure and activity was observed, as well as the possibility to predict the substitution patterns of new related active molecules.

Idioma originalInglés
Páginas (desde-hasta)239-257
Número de páginas19
PublicaciónArkivoc
Volumen2009
N.º2
DOI
EstadoPublicada - 28 feb 2009

Huella dactilar

Esters
Substitution reactions
Thermodynamic properties
Molecules
squaric acid
lawsone

Citar esto

Solorio-Alvarado, C. R., Peña-Cabrera, E., García-Soto, J., López-Godínez, J., González, F. J., & Álvarez-Hernández, A. (2009). 2-Hydroxynaphthoquinones. Synthesis, electrochemical study, and biological essays of activity. Arkivoc, 2009(2), 239-257. https://doi.org/10.3998/ark.5550190.0010.223
Solorio-Alvarado, César R. ; Peña-Cabrera, Eduardo ; García-Soto, Jesús ; López-Godínez, Juana ; González, Felipe J. ; Álvarez-Hernández, Alejandro. / 2-Hydroxynaphthoquinones. Synthesis, electrochemical study, and biological essays of activity. En: Arkivoc. 2009 ; Vol. 2009, N.º 2. pp. 239-257.
@article{db14ff9f17774dd08c793277df1baddb,
title = "2-Hydroxynaphthoquinones. Synthesis, electrochemical study, and biological essays of activity",
abstract = "The synthesis of nine 2-hydroxynaphthoquinones was achieved starting from squaric acid esters. The electrochemical and biological evaluations of these compounds were tested using the sea urchin ovules as a model. An interesting correlation between structure and activity was observed, as well as the possibility to predict the substitution patterns of new related active molecules.",
keywords = "Cancer, Naphthoquinones, Radical anion, Squaric esters",
author = "Solorio-Alvarado, {C{\'e}sar R.} and Eduardo Pe{\~n}a-Cabrera and Jes{\'u}s Garc{\'i}a-Soto and Juana L{\'o}pez-God{\'i}nez and Gonz{\'a}lez, {Felipe J.} and Alejandro {\'A}lvarez-Hern{\'a}ndez",
year = "2009",
month = "2",
day = "28",
doi = "10.3998/ark.5550190.0010.223",
language = "Ingl{\'e}s",
volume = "2009",
pages = "239--257",
journal = "Arkivoc",
issn = "1551-7004",
publisher = "Arkat USA",
number = "2",

}

Solorio-Alvarado, CR, Peña-Cabrera, E, García-Soto, J, López-Godínez, J, González, FJ & Álvarez-Hernández, A 2009, '2-Hydroxynaphthoquinones. Synthesis, electrochemical study, and biological essays of activity', Arkivoc, vol. 2009, n.º 2, pp. 239-257. https://doi.org/10.3998/ark.5550190.0010.223

2-Hydroxynaphthoquinones. Synthesis, electrochemical study, and biological essays of activity. / Solorio-Alvarado, César R.; Peña-Cabrera, Eduardo; García-Soto, Jesús; López-Godínez, Juana; González, Felipe J.; Álvarez-Hernández, Alejandro.

En: Arkivoc, Vol. 2009, N.º 2, 28.02.2009, p. 239-257.

Resultado de la investigación: Contribución a una revistaArtículo

TY - JOUR

T1 - 2-Hydroxynaphthoquinones. Synthesis, electrochemical study, and biological essays of activity

AU - Solorio-Alvarado, César R.

AU - Peña-Cabrera, Eduardo

AU - García-Soto, Jesús

AU - López-Godínez, Juana

AU - González, Felipe J.

AU - Álvarez-Hernández, Alejandro

PY - 2009/2/28

Y1 - 2009/2/28

N2 - The synthesis of nine 2-hydroxynaphthoquinones was achieved starting from squaric acid esters. The electrochemical and biological evaluations of these compounds were tested using the sea urchin ovules as a model. An interesting correlation between structure and activity was observed, as well as the possibility to predict the substitution patterns of new related active molecules.

AB - The synthesis of nine 2-hydroxynaphthoquinones was achieved starting from squaric acid esters. The electrochemical and biological evaluations of these compounds were tested using the sea urchin ovules as a model. An interesting correlation between structure and activity was observed, as well as the possibility to predict the substitution patterns of new related active molecules.

KW - Cancer

KW - Naphthoquinones

KW - Radical anion

KW - Squaric esters

UR - http://www.scopus.com/inward/record.url?scp=77951785722&partnerID=8YFLogxK

U2 - 10.3998/ark.5550190.0010.223

DO - 10.3998/ark.5550190.0010.223

M3 - Artículo

AN - SCOPUS:77951785722

VL - 2009

SP - 239

EP - 257

JO - Arkivoc

JF - Arkivoc

SN - 1551-7004

IS - 2

ER -

Solorio-Alvarado CR, Peña-Cabrera E, García-Soto J, López-Godínez J, González FJ, Álvarez-Hernández A. 2-Hydroxynaphthoquinones. Synthesis, electrochemical study, and biological essays of activity. Arkivoc. 2009 feb 28;2009(2):239-257. https://doi.org/10.3998/ark.5550190.0010.223